个人情况综述

李志鹏，男，1984年生，博士，教授，博士生导师，国家自然科学基金优秀青年科学基金获得者，主要围绕鹿类动物生物学与消化道微生物组开展原创性研究，主持国家自然科学基金面上等项目10余项，取得的原创性业绩如下：1）揭示了鹿角与瘤胃发育的分子与细胞基础，鉴定了调控鹿茸快速生长的关键基因、通路与酶，发现了与鹿科动物低癌症率有关的基因，阐明了鹿茸完全再生的细胞机制，发现并验证了调控骨组织修复的干细胞；揭示了驯鹿雌性长角、昼夜节律丧失、温顺、高效维生素D代谢等特殊性状的分子机制。2）首次系统阐明了7种反刍动物全消化道微生物与基因特征，鉴定出了8745个新的微生物基因组，揭示了鹿降解粗饲料的微生物学机制，明确了微生物调控幼鹿健康发育的机制，发现了影响鹿茸产量的靶标微生物与代谢物，创建了鹿茸增产的营养调控策略。以第一或通讯作者（含共同）在Science（4篇）、Science Advances、Microbiome等期刊发表SCI论文34篇，作为参与作者在Nature、Nature Communications、Science Bulletin、Science China Life Sciences等期刊发表论文8篇，成果入选2019年度“中国生命科学十大进展”和2020 年“中国农业科学重大进展”，荣获吉林省自然科学学术成果二等奖，第十六届吉林省青年科技奖特别奖（共三名），入选吉林省拔尖创新人才第三层。

学习工作简历

一、教育经历

2002.09-2007.07, 中国农业大学, 动物医学院, 学士

2010.09-2013.07, 中国农业科学院研究生院，野生动植物保护与利用，硕士

2017.09-2020.09, 南京农业大学，动物营养与饲料科学，博士

二、工作经历

2007.07-2013.12，中国农业科学院特产研究所，研究实习员

2014.01-2018.12，中国农业科学院特产研究所，助理研究员

2019.01-2020.08，中国农业科学院特产研究所，副研究员

2020/09-至今，   吉林农业大学，教授

教学工作

动物生态学，鹿生产学

主要科研方向

（1）鹿茸生长发育与消化道微生物调控

（2）鹿类动物生物学

主要科研项目

（1）国家自然科学基金优秀青年科学基金，2022-2024，主持

（2）吉林农业大学高层次人才队伍建设专项，2021-2024，主持

（3）国家自然科学基金面上项目，2021-2024，主持

（4）国家自然科学基金青年基金，2016-2018，主持

（5）吉林省自然科学基金面上项目，2017-2019，主持

（6）吉林省科技攻关项目，2019-2021，主持

（7）中央级基本科研业务费，2019，主持

（8）国家重点研发计划子课题，2019-2021，主持

（9）中国科协优秀中外青年交流计划，2020，主持

主要科研成果

（1）2015年，吉林省自然科学学术成果奖二等奖，第1

发表文章

[1].Li ZP, Liu HL, Jin CA, Cui XZ, Jing Y, Yang FH, Li GY, Wright A-DG: Differences in the methanogen population rxist in sika deer (Cervus nippon) fed different diets in China. Microbial Ecology 2013, 66(4):879-888.

[2].Li ZP, Liu HL, Li GY, Bao K, Wang KY, Xu C, Yang YF, Yang FH, Wright A-DG: Molecular diversity of rumen bacterial communities from tannin-rich and fiber-rich forage fed domestic Sika deer (Cervus nippon) in China. BMC Microbiology 2013, 13(1):151.

[3].Li Z, Zhang Z, Xu C, Zhao J, Liu H, Fan Z, Yang F, Wright A-DG, Li G: Bacteria and methanogens differ along the gastrointestinal tract of Chinese roe deer (Capreolus pygargus). PLoS ONE 2014, 9(12):e114513.

[4].Li Z, Wright A-DG, Liu H, Bao K, Zhang T, Wang K, Cui X, Yang F, Zhang Z, Li G: Bacterial community composition and fermentation patterns in the rumen of sika deer (Cervus nippon) fed three different diets. Microbial Ecology 2015, 69(2):307-318.

[5].Li Z, Wright A-DG, Liu H, Fan Z, Yang F, Zhang Z, Li G: Response of the rumen microbiota of sika deer (Cervus nippon) fed different concentrations of tannin rich plants. PLoS ONE 2015, 10(5):e0123481.

[6].Li Z, Wright A-DG, Si H, Wang X, Qian W, Zhang Z, Li G: Changes in the rumen microbiome and metabolites reveal the effect of host genetics on hybrid crosses. Environmental Microbiology Reports 2016, 8(6):1016-1023.

[7].Li Z, Henderson G, Yang Y, Li G: Diversity of formyltetrahydrofolate synthetase genes in the rumens of roe deer (Capreolus pygargus) and sika deer (Cervus nippon) fed different diets. Canadian Journal of Microbiology 2017, 63(1):11-19.

[8].Li Z, Lin Z, Ba H, Chen L, Yang Y, Wang K, Qiu Q, Wang W, Li G: Draft genome of the reindeer (Rangifer tarandus). GigaScience 2017, 6(12):1-5.

[9].Li Z, Wright A-DG, Yang Y, Si H, Li G: Unique bacteria community composition and co-occurrence in the milk of different ruminants. Scientific Reports 2017, 7(1):40950.

[10].Qian W, Li Z, Ao W, Zhao G, Li G, Wu J: Bacterial community composition and fermentation in the rumen of Xinjiang brown cattle (Bos taurus), Tarim red deer (Cervus elaphus yarkandensis), and Karakul sheep (Ovis aries). Canadian Journal of Microbiology 2017, 63(5):375-383.

[11].Ba H, Li Z, Yang Y, Li C: Development of diagnostic SNP markers to monitor hybridization between sika deer (Cervus nippon) and wapiti (Cervus elaphus). G3: Genes|Genomes|Genetics 2018, 8(7):2173–2179.

[12].Li Z, Wang X, Zhang T, Si H, Nan W, Xu C, Guan L, Wright A-DG, Li G: The development of microbiota and metabolome in small intestine of sika deer (Cervus nippon) from birth to weaning. 2018, 9.

[13].Yan XT, Yan BY, Ren QM, Dou JJ, Wang WW, Zhang JJ, Zhou JW, Long RJ, Ding LM, Han J et al: Effect of slow-release urea on the composition of ruminal bacteria and fungi communities in yak. Animal Feed Science and Technology 2018, 244:18-27.

[14].Chen L, Qiu Q, Jiang Y, Wang K, Lin Z, Li Z, Bibi F, Yang Y, Wang J, Nie W et al: Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits. Science 2019, 364(6446):eaav6202.

[15].Li Z, Si H, Nan W, Wang X, Zhang T, Li G: Bacterial community and metabolome shifts in the cecum and colon of captive sika deer (Cervus nippon) from birth to post weaning. FEMS Microbiology Letters 2019, 366(4):fnz010.

[16].Li Z, Wang X, Zhang T, Si H, Xu C, Wright A-DG, Li G: Heterogeneous development of methanogens and the correlation with bacteria in the rumen and cecum of sika deer (Cervus nippon) during early life suggest different ecology relevance. BMC Microbiology 2019, 19(1):129.

[17].Lin Z, Chen L, Chen X, Zhong Y, Yang Y, Xia W, Liu C, Zhu W, Wang H, Yan B et al: Biological adaptations in the Arctic cervid, the reindeer (Rangifer tarandus). Science 2019, 364(6446):eaav6312.

[18].Qian W, Ao W, Jia C, Li Z: Bacterial colonisation of reeds and cottonseed hulls in the rumen of Tarim red deer (Cervus elaphus yarkandensis). Antonie van Leeuwenhoek 2019, 112(9):1283-1296.

[19].Wang Y, Zhang C, Wang N, Li Z, Heller R, Liu R, Zhao Y, Han J, Pan X, Zheng Z et al: Genetic basis of ruminant headgear and rapid antler regeneration. Science 2019, 364(6446):eaav6335.

[20].de Jong MJ, Li Z, Qin Y, Quéméré E, Baker K, Wang W, Hoelzel AR: Demography and adaptation promoting evolutionary transitions in a mammalian genus that diversified during the Pleistocene. Molecular Ecology 2020, 29(15):2777-2792.

[21].Li Z, Mu C, Xu Y, Shen J, Zhu W: Changes in the solid-, liquid-, and epithelium-associated bacterial communities in the rumen of hu lambs in response to dietary urea supplementation. Frontiers in Microbiology 2020, 11.

[22].Li Z, Shen J, Xu Y, Zhu W: Metagenomic analysis reveals significant differences in microbiome and metabolic profiles in the rumen of sheep fed low N diet with increased urea supplementation. FEMS Microbiology Ecology 2020, 96(10):fiaa117.

[23].Li ZP, Wang XX, Alberdi A, Deng JB, Zhong ZY, Si HZ, Zheng CL, Zhou HL, Wang JM, Yang YF et al: Comparative microbiome analysis reveals the ecological relationships between rumen methanogens, acetogens, and their hosts. Frontiers in microbiology 2020, 11(1311).

[24].Ren Q, Si H, Yan X, Liu C, Ding L, Long R, Li Z, Qiu Q: Bacterial communities in the solid, liquid, dorsal, and ventral epithelium fractions of yak (Bos grunniens) rumen. MicrobiologyOpen 2020, 9(2):e963.

[25].Shen J, Li Z, Yu Z, Zhu W: Effects of dietary replacement of soybean meal with dried distillers grains with solubles on the microbiota occupying different ecological niches in the rumen of growing Hu lambs. Journal of Animal Science and Biotechnology 2020, 11(1):93.

[26].Liu C, Gao J, Cui X, Li Z, Chen L, Yuan Y, Zhang Y, Mei L, Zhao L, Cai D et al: A towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe. Science Advances 2021, 7(12):eabe9459.

[27].Pan X, Cai Y, Li Z, Chen X, Heller R, Wang N, Wang Y, Zhao C, Wang Y, Xu H et al: Modes of genetic adaptations underlying functional innovations in the rumen. Science China Life Sciences 2021, 64(1):1-21.

[28].Si H, Han Y, Liu H, Lou Y, Li Z: Effects of rumen-protected arginine supplementation on the plasma amino acids and gut microbiota of sika deer (Cervus nippon). Animal Feed Science and Technology 2021, 273:114828.

[29].Si H, Liu H, Nan W, Li G, Li Z, Lou Y: Effects of arginine supplementation on serum metabolites and the rumen bacterial community of sika deer (Cervus nippon). Frontiers in Veterinary Science 2021, 8.

[30].Xie F, Jin W, Si HZ, Yuan Y, Tao Y, Liu JH, Wang XX, Yang CJ, Li QS, Yan XT et al: An integrated gene catalog and over 10,000 metagenome-assembled genomes from the gastrointestinal microbiome of ruminants. Microbiome 2021, 9(1):137.

[31].Yin Y, Fan H, Zhou B, Hu Y, Fan G, Wang J, Zhou F, Nie W, Zhang C, Liu L et al: Molecular mechanisms and topological consequences of drastic chromosomal rearrangements of muntjac deer. Nature Communications 2021, 12(1):6858.

[32].Chen C, Yin Y, Li H, Zhou B, Zhou J, Zhou X, Li Z, Liu G, Pan X, Zhang R et al: Ruminant-specific genes identified using high-quality genome data and their roles in rumen evolution. Science Bulletin 2022, 67(8):825-835.

[33].Jiang Q, Lin L, Xie F, Jin W, Zhu W, Wang M, Qiu Q, Li Z, Liu J, Mao S: Metagenomic insights into the microbe-mediated B and K2 vitamin biosynthesis in the gastrointestinal microbiome of ruminants. Microbiome 2022, 10(1):109.

[34].Si H, Li S, Nan W, Sang J, Xu C, Li Z: Integrated transcriptome and microbiota reveal the regulatory effect of 25-hydroxyvitamin D supplementation in antler growth of sika deer. Animals 2022, 12(24):3497.

[35].Yan X, Si H, Zhu Y, Li S, Han Y, Liu H, Du R, Pope PB, Qiu Q, Li Z: Integrated multi-omics of the gastrointestinal microbiome and ruminant host reveals metabolic adaptation underlying early life development. Microbiome 2022, 10(1):222.

[36].Yuan Y, Sun D, Qin T, Mao S, Zhu W, Yin Y, Huang J, Heller R, Li Z, Liu J et al: Single-cell transcriptomic landscape of the sheep rumen provides insights into physiological programming development and adaptation of digestive strategies. Zoological Research 2022, 43(4):634-647.

[37].Qin T, Zhang G, Zheng Y, Li S, Yuan Y, Li Q, Hu M, Si H, Wei G, Gao X et al: A population of stem cells with strong regenerative potential discovered in deer antlers. Science 2023.

教材及专著

获奖信息

（1）2014年，中国农业科学院优秀硕士论文

（2）2015年，吉林省自然科学学术成果奖二等奖，第1

（3）2017年，吉林市优秀青年科技专家

（4）2017年，第十二届国际基因组大会GigaScience前沿科技奖三等奖

（5）2019年，第七届吉林省拔尖创新人才第三层次

（6）2021年，第十六届吉林省青年科技奖特别奖

（7）2023年，2022年中国农学会青年科技奖

社会兼职

（1）吉林省动物学会第十三届理事会副理事长

（2）全国动物营养指导委员会特产动物营养分会委员

（3）Journal of Genetics and Genomics 青年编委